Chaga Gold™ (Inonotus obliquus mushroom) - $24.95

 

Chaga Gold™ from Aloha Medicinals is the absolute best Chaga product available anywhere in the world today – Guaranteed! Chaga Gold™ is a combination of 50% Sustainably Harvested Wild Chaga from White Birch growing in the pristine Upper Peninsula of Michigan and 50% of the top quality, Certified Organic all-natural cultivated Chaga grown in America by Aloha Medicinals, the World’s largest grower of cultivated Chaga. Each bottle contains 525 mg of only pure Chaga in a vegetarian capsule – nothing else.

Chaga Gold™ is tested and Certified by Independent Third Party FDA Certified Labs to contain the HIGHEST levels of Betulinic Acid of ANY Chaga product on the market today! Please click here to see the attached analysis for Independent verification that Chaga Gold™ is Guaranteed to containover 1% Betulinic Acid content! Why buy imported chaga when Chaga Gold™ is allAmerican – and the Most Potent chaga available today!

Chaga has a long history of use throughout Eastern Europe and Asia, with the majority of the world’s supply collected in Siberia. Unfortunately, Chaga tends to accumulate radioactive minerals, and since the Fukushima disaster the wild collected Chaga from Siberia is unsafe to consume.

Aloha Medicinals tests every batch of Chaga Gold™ to ensure there are no radioactive compounds present.  

Chaga Gold™ is guaranteed 100% Safe!

This is the only Chaga in the world guaranteed to be 100% free of radiation!

Chaga Gold™  is the only Chaga on the market today that comes with Independent Third Party Analysis – Certified to be 100% free of all radioactive and all other contamination! Click here to see the analysis. We are so sure you will be happy with Chaga Gold™ we gladly offer our 100% Satisfaction Guarantee. If you are unhappy with Chaga Gold™ for any reason, simply return it for a full refund. What do you have to lose? For your optimum health - Try Chaga Gold™ today!

Each bottle of Chaga Gold™ contains a Full One Month Supply – 90 capsules containing 525 mg ea. $24.95 per bottle

 

Radiation Analysis [pdf]

 

Betulinic Acid Analysis [pdf]

 

Polysaccharides Analysis [pdf]

 

Certificate of Analysis [pdf]

 

Chaga (Inonotus obliquus mushroom) Information

 

Information reprinted with permission from the excellent new book by Martin Powell titled “Medicinal Mushrooms, a Clinical Guide” page 62-64. This reprinted section  is intended for informational value only and is not intended to represent any claims for medical usage. If you have any medical condition – please discuss with  your doctor before using any supplements.

Japanese name – Kabanoanatake

Chinese name - Bai Hua Rong

English name – Chaga

I. obliquus grows widely in the forests of Eastern Europe and Russia on several trees, including birch, alder and spruce, where it appears as a sterile growth or conk on the trunk of the tree. The fruiting body is reported to be found growing nearby but is extremely rare in nature.

Traditionally only the I. obliquus growing on birch trees was used, as a tea in the treatment of cancers including inoperable breast cancer, hip, gastric, parotid, pulmonary, stomach, skin, rectal and Hodgkins disease¹ and I. obliquus is recorded as a miraculous cure for cancer in Solzhenitsyn’s semi-autobiographical 1967 novel, the “Cancer Ward”.

The wisdom of using birch grown I. obliquus is supported by the finding that one of its key components is the triterpene betulinic acid, which occurs naturally in a number of plants but primarily in the bark of the white birch (Betula pubescens – seen as the tree of life and fertility in many Eastern European and Siberian myths) from which it gets its name. I. obliquus growing on the birch trees takes up high concentrations of betulinic acid from the bark of the trees, making it and its derivatives available in an absorbable form.

Betulinic acid has been shown to induce mitochondrial apoptosis in different cancer cell lines and inhibit the enzyme topoisomerase², which is essential for the unwinding and winding of the DNA strands in cell replication. In addition it possesses anti-retroviral, anti-parasitic and anti-inflammatory properties³. It is currently being developed as an anti-cancer agent through the Rapid Access to Intervention Development program of the US National Cancer Institute and is also a major contributor to the anti-cancer action of mistletoe⁴.

Other important components of I. obliquus include polysaccharides and sterols. Its high phenolic content gives it exceptional antioxidant properties and a melanin complex has also been identified as having significant antioxidant and genoprotective properties ^5,6.

Widely used in Poland and Russia as a folk remedy against cancer⁷, I. obliquus is now attracting increasing interest among practitioners with its combination of immune supporting polysaccharides and components with direct anti-cancer activity, especially betulinic acid derivatives.

In vitro studies on betulinic acid have shown it to be highly effective against a wide variety of cancer cells: human melanoma, neuroectodermal (neuroblastoma, medulloblastoma, Ewing’s sarcoma” and malignant brain tumours, ovarian cancer, human leukaemia HL-60 cells and malignant head and neck squamous cell cancers, including those derived from therapy-resistant and refractory tumours^8,9. However, it was found to have no effect on epithelial tumours, such as breast cancer, colon cancer, small cell lung cancer and renal cell cancer as well as T-cell leukaemia cells. Its anti-tumour activity has been related to its direct effects on mitochondria and induction of apoptosis, irrespective of cells p53 status¹⁰.

Clinically betulinic acid’s action against brain cancer cells is particularly interesting and it is noteworthy that in one study it exerted cytotoxic activity against primary tumour cells cultured from patients in 4 of 4 medulloblastoma-tumour samples tested and in 20 of 24 glioblastoma-tumour samples¹¹. It also shows great promise in combination with radiotherapy, exhibiting a strictly additive mode of growth inhibition in combination with radiation in human melanoma cells in one study and acting as a radiosensitizer in head and neck squamous cell cancers in another^12,13.

In vivo studies confirm its anti-cancer action as well as a complete absence of systemic toxicity in rodents⁸.

ANTI-VIRAL – I. obliquus has traditionally been used to treat a number of viral conditions and betulinic acid analogs have been shown to disrupt assembly and budding of the HIV-1 virus and viral fusion to the cell membrane⁹.

CLINICAL SUMMARY

Main Therapeutic Applications – Cancer, Anti-viral, antioxidant

Key Component – Betulinic acid derivatives

 

REFERENCES

1. Plants used against cancer. Hartwell J.L. 1982. Quartermain Pubs: Lawrence, Mass. P.694

2. Betulinic acid, a potent inhibitor of eukaryotic topoisomerase I: identification of the inhibitory step, the major functional group responsible and development of more potent derivatives. Chowdhury A.R, Mandal S, Mittra B, Sharma S, Mukhopadhyay S, Majumder H.K. Medical Science Monitor. 2002: 8(7);254-65

3. Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice. De Sá M.S, Costa J.F, Krettli A. U, Zalis M.G, Maia G.L,Sette I.M, Camara Dde A. Filho J.M, Guilietti-Harley A.M, Ribeiro Dos Santos R, Soares M.B. Parsitol Rers.2009;105(1);275-9

4. Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L. Jäger S. Winkler K, Pfüller U, Schefler A. Planta Med. 2007;73(2):157-62

5. Antioxidant small phenolic ingredients in Inonotus obliquus (persoon) Pilat (Chaga). Nakajima Y. Sato Y, Konishi t.Chem Pharm Bull (Tokyo).2007;55(8);
1222-6

6. Melanin complex from medicinal mushroom Inonotus obliquus (Per,:Fr.) Pilat (Chaga)(Aphyllophoromycetideae). Bisko N.A, Mitropolskaya N.Y, Ikonnikova N.V. Int J Med Mushr.2002;4(2);139-145

7. Study of anticarcinogenic properties of Poria oblique Patalog. Nazarewicz T, Konopa J. Pol. 1961;1:80-82

8. Betulinic acid, a natural compound with potent anticancer effects. Mullauer F.B, Kessler J.H, Medema J. P. anticancer Drugs.2010;21(3):215-27, 2010;24(1);90-114

9. Betulinic acid induces apoptosis in human neuroblastoma cell lines. Schmidt M.L, Kuzmanoff K.L, Ling-Indeck L, Pezzuto J.M. European Journal of Cancer.1997;33(12):2007-10

10. Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cncer and HIV infection. Cichewicz R.H, Kouzi S.A. Med Res Rev.2004;24(1);90-114

11. Betulinic acid: a new cytotoxic agent against malignant brain-tumour cells. Fulda S, Jeremias I, Steiner H.H, Pietsch T, Dabatin K.M. Int J Cancer. 1999;82(3):435-41

12. Effect of betulinic acid alone and in combination with irradiation in human melanoma cells. Selzer E, Pimentel E, Wacheck V, et at. The Journal of Investigative Dermatology.2000;114(5):935-40

13. Betulinic acid – a radiosensitizer in head and neck Squamous cell carcinoma cell lines. Eder-Czembirek c, Erovic B.M, Czembirec C, Brunner M, Selzer E, Pötter R, Thurnher D. Strahlenther Onkol. 2010

14. Medicinal Mushrooms. An exploration of tradition, healing and culture. Hobbs C. 1986. Pub Botanica Press, Williams

 

 

 

 

 

 

 

 

 

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