How tumors go undetected by the body

Scientists have made a key discovery in understanding why tumours may go undetected by the immune system.

They remain untreated by the body's own natural defences and therefor can cause tumors to expand. The findings could lead to new treatments for tumors. Under normal circumstances, the immune system creates sustained inflammation around a dangerous pathogen or injury which tells the body that there is a problem. However, in the case of tumours, certain cellular mechanisms counteract inflammation which can cause the tumour to go undetected, making it even harder for the body to expel.

The researchers at King's College London, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), discovered that regulatory T cells can reverse the role of a key immune cell called a macrophage which is normally involved in causing inflammation. Regulatory T cells are cells that regulate the immune system to stop it over-responding to every external stimulus and only deal with genuinely harmful pathogens or injuries.

The research shows that they can achieve this by encouraging macrophages to instead dampen down the inflammatory response that is automatically induced by all possible threats to the body, even those that turn out to be harmless.

Dr Leonie Taams, research leader explains: "A relatively harmless stimulus, such as a small cut, will automatically be treated by the body as something dangerous and will cause macrophages to promote inflammation. We discovered that it is then the regulatory T cells' responsibility to make the macrophages promote anti-inflammation to counteract the initial response, as it is not a real danger. This helps keep the immune system stable and prevents the body over-reacting to everything in its environment.

"However problems can occur with tumours, where many regulatory T cells promoting a strong anti-inflammatory response are present. Neutralising an inflammatory response in this scenario can cause the tumour to fall under the radar of the body's immune system and 'trick' it into believing that there is no problem.

"We hope to be able to use this new knowledge about the relationship between regulatory T cells and macrophages to find more effective treatments for tumours. Interestingly, we also hope to use the same knowledge to achieve the opposite result and block chronic inflammation such as that which occurs in rheumatoid arthritis."

Source: Science Daily (Nov. 21, 2007)

 

 

Our Money Back Guarantee

We are so certain you will be helped by our products that we offer a Full 100% money back Guarantee! If you are not completely satisfied with your Aloha Medicinals purchase, you may return all unused product to us for a full refund. Call Toll Free (877) 835-6091 for full details on returns.

 


For all of you formulators - Aloha Medicinals also offers bulk powder ingredients for use in your formulations, which are 100% USDA and EU Certified Organic. Call our customer service representative at (775) 886-6300 for more information and to place your order today!

 

 

Bookmark this page into your favorite bookmark manager. Or press (CTRL-D)

NOTE: Regardless of how our products may be used in other countries, or anything that you may have heard or read about Aloha Medicinals products, under FDA law in the United States it is illegal for a manufacturer to make any medical claims for health supplements. None of the products offered for sale on our website or direct to retail consumers are intended to be used in the treatment or mitigation of any disease state. All statements made by Aloha Medicinals Inc. are intended for informational purposes only. The statements made here have not been evaluated by the FDA, and our products are not intended to diagnose, treat, cure or prevent any disease. Health decisions are much too important to be made without the advice of a health care practitioner. As with any dietary or herbal supplement, you should advise your health care practitioner of the use of this product. If you are nursing, pregnant, or considering pregnancy, you should consult your health care practitioner prior to using any health supplement product.